Reference Library
What is the Reference Library?
Keeping current with the retina literature is, for most, an ongoing, futile effort. New journals are constantly being introduced, and existing journals keep getting thicker and thicker. Researching a topic on PubMed doesn’t allow you to spot key references or quickly digest what’s new globally on a topic of interest. And remembering what you’ve read a few weeks later (or even after you’ve turned the page to the next article) is a struggle.
To address these concerns, we pull key clinical references from 24 major ophthalmic and retinal journals each month (click here for the journal list). Although we can’t provide the journal article PDF due to copyright issues, we provide a single-line citation with a brief summary of the article’s main points. Our goal is to capture all major clinically relevant references.
Please contact us if we’re missing any key references or if any reference is mis-summarized or cited.
Want to Automatically Receive Our Monthly Journal Article Summaries?
That’s easy! Just subscribe to the Retina World Congress’s monthly email blast here.
How is the Reference Library integrated into the Image Library?
At the top of most Image Library folders is a ___References Word document containing the annotated bibliography for that topic. Every month, we file key articles into the appropriate Retina Rocks folder(s) and update this file. Key articles are located at the top of the list. This allows for a rapid snapshot and review of the literature while also looking through our multimedia images. Some seemingly unrelated references are included in each folder to aid in differential diagnosis or to learn about similar findings in other disorders.
Key Retina Journal Articles of the Month
Here is the current month's snapshot of key retina journal articles
Monthly Archives
Anti-VEGF versus laser therapy for retinopathy of prematurity: a systematic review and meta-analysis focusing on recurrence patterns and retreatment needs
Int J Retina Vitreous. 2026 Jan 30;12(1):30. doi: 10.1186/s40942-026-00810-9.
Systematic review and meta-analysis ROP: Anti-VEGF effective for Zone 1, but Zone II has higher recurrence and re-treatment risk.
Efficacy And Safety Of Suprachoroidal Triamcinolone Acetonide In Mixed Etiology Noninfectious Cystoid Macular Edema
Retina. 2026 Feb 1;46(2):240-248. doi: 10.1097/IAE.0000000000004688.
Suprachoroidal triamcinolone for uveitic CME: Effective and safe, 12% increased IOP.
Multimodal Imaging And Long-Term Treatment Outcomes Of Relentless Placoid Chorioretinitis
Retina. 2026 Feb 1;46(2):249-254. doi: 10.1097/IAE.0000000000004674.
Relentless placoid chorioretinitis. Multimodal imaging and long-term outcomes: All became quiescent with immunomodulatory therapy with stable or improved VA. Retrospective, 11 eyes.
Visual And Anatomic Outcomes Of Vitrectomy For Myopic Maculoschisis With And Without Macular Detachment: A Case-Control Study
Retina. 2026 Feb 1;46(2):291-300. doi: 10.1097/IAE.0000000000004689.
PPV myopic maculoschisis. Presence of macular detachment didn’t affect postop VA or anatomic results. Retrospective, 38 eyes.
Treatment outcomes of switching to aflibercept 8 mg in previously-treated neovascular age-related macular degeneration
Graefes Arch Clin Exp Ophthalmol. 2026 Jan;264(1):81-89. doi: 10.1007/s00417-025-06979-3.
nAMD Switch to Eylea HD extends treatment interval while maintaining VA and reducing CMT and PED height. Retrospective, 121 eyes.
Characterization of subretinal hyperreflective material and short-term visual acuity in patients with neovascular age related macular degeneration after loading dose with antiangiogenics
Graefes Arch Clin Exp Ophthalmol. 2026 Feb;264(2):465-471. doi: 10.1007/s00417-025-06986-4.
nAMD SHRM Baseline characteristics have short-term VA prognosis, including low reflectivity, non-homogeneity, reduced width, and presence of ELM-EZ.
Long-Term Metformin Use and Reduced Risk of Age-Related Macular Degeneration: A Large Database Study
Ophthalmol Retina. 2026 Feb;10(2):135-141. doi: 10.1016/j.oret.2025.07.018.
Metformin is associated with reduced AMD risk. Retrospective, TriNetX database.
Exudative Macular Neovascularization Before Visible Pigmentation In Macular Telangiectasia Type-2 (Mactel)
Retina. 2026 Feb 1;46(2):318-330. doi: 10.1097/IAE.0000000000004716.
MacTel2 Exudative MNV before visible pigmentation. Retrospective, 16 eyes.
Large Retinal Capillary Aneurysm: Clinical Features, Multimodal Imaging Characteristics, and Treatment Outcomes of Primary and Secondary Lesions
Retina. 2026 Feb 1;46(2):351-360. doi: 10.1097/IAE.0000000000004665.
Large retinal capillary aneurysms: Clinical features, multimodal imaging, treatment outcomes of primary and secondary lesions. Retrospective, 34 eyes.
Macular Thickness Fluctuation as a Biomarker: Impact on Visual Acuity Following Antivascular Endothelial Growth Factor Therapy for Diabetic Macular Edema
J Vitreoretin Dis. 2025 Oct 31:24741264251383388. doi: 10.1177/24741264251383388.
DME anti-VEGF CST fluctuation is independently associated with worse VA. Retrospective, 499 eyes.
Systemic Thromboembolic Outcomes In Young Patients After Retinal Vein Occlusions
Retina. 2026 Feb 1;46(2):229-239. doi: 10.1097/IAE.0000000000004700.
CRVO in 18-50YO and no baseline identifiable vascular or hypercoag risk factors are at subsequent increased risk for venous thrombosis and CVA but not MI. With editorial. Retrospective, TriNetX database.
Outcomes of Complex PVR Retinal Detachment Repair With and Without Intravitreal Methotrexate at a Single Tertiary Care Center
Ophthalmic Surg Lasers Imaging Retina. 2026 Feb;57(2):83-92. doi: 10.3928/23258160-20250826-01.
Complex PVR RD repair MTX no effect at any time point in single-surgery reattachment. Retrospective, MEEI, 136 eyes.
Novel Bilateral Geographic Atrophy Phenotype Associated With CRX Mutation
J Vitreoretin Dis. 2025 Oct 22:24741264251386364. doi: 10.1177/24741264251386364.
Case of novel CRX mutation simulating bilateral AMD GA, but without drusenoid deposits.
Long-Term Outcomes and Patient Experiences With the Argus II Retinal Prosthesis System
J Vitreoretin Dis. 2025 Oct 4:24741264251376042. doi: 10.1177/24741264251376042.
Argus II long-term outcomes and patient experiences. Retrospective, 13 patients.
Type 4 Macular Neovascularization: A New Member of the Optical Coherence Tomography Classification of Neovascularization Age-Related Macular Degeneration
Retina. 2026 Feb 1;46(2):209-219. doi: 10.1097/IAE.0000000000004664.
AMD Type 4 MNV Novel lesion with mixed types 1 and 2 MNV, anastomotic intraretinal NV network with inner and pre-retinal proliferation-fibrosis. Poor VA. Retrospective, 11 eyes.
Rates of endophthalmitis in prefilled versus nonprefilled syringes for intravitreal injections: a systematic review and meta-analysis
Ophthalmol Retina. 2026 Apr 11:S2468-6530(26)00105-3. doi: 10.1016/j.oret.2026.03.008.
Systematic review and meta-analysis: Prefilled syringes 47-48% lower endophthalmitis risk vs non-prefilled.
Risk of Alzheimer Disease and Related Dementia after Retinal Vascular Occlusion: A Nationwide Cohort Analysis
Ophthalmol Retina. 2026 Feb;10(2):117-127. doi: 10.1016/j.oret.2025.10.017.
Retinal vascular occlusion associated with moderate increased dementia risk. Retrospective, Taiwan national health database (with editorial).
Peripapillary Retinoschisis: The Expanded Spectrum and New Insights From Multimodal Imaging
Am J Ophthalmol. 2026 Feb:282:26-40. doi: 10.1016/j.ajo.2025.10.017.
Peripapillary retinoschisis expanded spectrum: Non-glaucomatous ON congenital disc anomalies, Peripap abnormalities(coloboma, peripapillary atrophy), peripapillary disease (PPS, PP-CNV), Vit interface (myopia, vit-disc traction), idiopathic.
Pentosan Polysulfate Maculopathy Following Subcutaneous Injections for Arthritis
JAMA Ophthalmol. 2026 Feb 1;144(2):185-191. doi: 10.1001/jamaophthalmol.2025.5069.
Pentosan polysulfate maculopathy following subcutaneous injections for arthritis. Toxicity at much lower doses than oral due to 10-fold increased bioavailability; one with AVLs. Retrospective, 3 cases.
Risk of Sight-Threatening Diabetic Retinopathy with Glucagon-Like Peptide-1 Receptor Agonist Use in Routine Clinical Practice: Comparative Effectiveness of Semaglutide, Dulaglutide, Liraglutide, and Exenatide
Ophthalmol Retina. 2026 Feb;10(2):142-151. doi: 10.1016/j.oret.2025.07.019.
GLP1-RA agents similar risk of sight-threatening retinopathy after drug initiation. Retrospective, MC database.
The association between treatment method, microbiological findings, and visual acuity in endophthalmitis patients: A retrospective, multi-centered study
Eye (Lond). 2026 Feb;40(3):406-411. doi: 10.1038/s41433-025-04125-1.
Endophthalmitis (endogenous and exogenous). No VA differences between tap-inject vs PPV or between culture-positive or negative cases at any point up to 1-year FU. Retrospective, 111 patients.
Pneumatic retinopexy in the real world: A critical reappraisal of the PIVOT trial
Eye (Lond). 2026 Feb;40(2):163-164. doi: 10.1038/s41433-025-04143-z.
Editorial Pneumatic retinopexy (PnRP) in the real world: Critical reappraisal of PIVOT trial PnRP true primary success in 72%; VA benefit largely from lens status. Restrictive inclusion criteria.
